Journal of Clinical Trials and Experimental Investigations https://jctei.com/index.php/jctei <p>The <strong>“Journal of Clinical Trials and Experimental Investigations (Abbreviation: J Clin Trials Exp Investig)" (e-ISSN 2822-5090)</strong> is an independent, quarterly, peer-reviewed, double-blind, open-access international general medical journal founded in January 2022. It is published four times a year (March, June, September, and December). This journal publishes Original Articles, Reviews, Short communications, Case reports, Letters to the Editor, Opinion papers, Technical notes, and Editorials. Articles are selected and published following a rigorous analysis, according to internationally accepted standards. The journal is open to scholars, as well as all members of the medical community, expressing interest in using this forum to publish their work. No fee is charged from the authors during the article evaluation and publication process. The Journal of Clinical Trials and Experimental Investigations is the official journal of the Silvan Academy of Surgery. The journal is non-profit and doesn't accept advertisements. The official language is English.</p> en-US <p><img src="https://www.jctei.com/index.php/jctei/management/settings/public/site/images/by-nc-lisans.png" alt="" width="114" height="40" /> The journal is licensed under a <a href="https://creativecommons.org/licenses/by/4.0/deed.en" target="_blank" rel="license noopener">Attribution4.0 International (CC BY 4.0)</a>.</p> editor@jctei.com (Editor/ Prof. Dr. Mehmet Hanifi Okur) unicos@unicosmedicine.com (Publisher /Unico's Medicine Publishing House // Publisher Adress: Başakşehir kayabaşı Mah. Evliya Çelebi Cad. Emlak Konut Evl. A2;28. 34480 Başakşehir - Istanbul/Turkey) Sat, 30 Mar 2024 00:00:00 +0300 OJS 3.3.0.11 http://blogs.law.harvard.edu/tech/rss 60 Evaluation of oral cancer knowledge and awareness among patients at a periodontology clinic https://jctei.com/index.php/jctei/article/view/96 <p><strong>Objective:</strong> The current study was designed to assess the extent of knowledge and awareness regarding oral cancer among patients presenting to the periodontology clinic.</p> <p><strong>Materials and methods:</strong> The research was carried out through in-person interviews with 510 volunteer patients, utilizing a questionnaire format. The questionnaire comprised two sections: the first section contained seven demographic questions addressing gender, age, education level, smoking habits, alcohol consumption, frequency of tooth brushing, and a family history of cancer. The second section consisted of 13 items aimed at evaluating the participants’ awareness and knowledge concerning oral cancer.</p> <p><strong>Results: </strong>A majority of the participants, accounting for 68.6%, reported that they had not been previously aware of oral cancer. The study revealed a significant association between the levels of awareness about oral cancer and variables such as gender, education level, and oral hygiene practices (p&lt;0.05). An increase in education level corresponded with heightened awareness, with men exhibiting greater awareness than women. The perception of risk factors among the patients varied, with smoking being recognized as a risk factor by 72% of the participants, followed by poor oral hygiene at 66.3%, a family history of cancer at 58.4%, alcohol consumption at 56.5%, malnutrition at 55.5%, and excessive sun exposure at 42.5%. Non-healing oral sores were identified as the most recognized sign of cancer, noted by 65% of the respondents. When faced with such symptoms, a significant portion of the patients, 72.4%, indicated they would consult a dentist. Meanwhile, 16.5% would choose to see an ENT (ear, nose and throat) specialist, and a smaller segment, 6.1%, would approach a general practitioner.</p> <p><strong>Conclusions: </strong>This study revealed that societal knowledge and awareness of oral cancer are significantly lacking. The implementation of educational programs to enhance individual knowledge and awareness of oral cancer, coupled with the consistent and thorough examination of the oral mucosa by relevant healthcare professionals, including dentists and ENT specialists, could facilitate the prevention of the disease and promote its early diagnosis.</p> Gulnur Saglam, Ahmet Dag Copyright (c) 2024 Journal of Clinical Trials and Experimental Investigations https://creativecommons.org/licenses/by/4.0 https://jctei.com/index.php/jctei/article/view/96 Mon, 25 Mar 2024 00:00:00 +0300 Oral rehabilitation of a pediatric patient with osteogenesis imperfecta type VII: A case report https://jctei.com/index.php/jctei/article/view/102 <p>Osteogenesis imperfecta (OI), also known as glass bone disease, is associated with mutations in COL1A1 and COL1A2, which encode collagen type I chains, and is inherited in an autosomal dominant manner. However, as the molecular structure of the disease progresses, new autosomal recessive types have been identified. Type VII has recently been defined as a type of OI caused by the mutation of a fatal recessively inherited cartilage-associated protein (CRTAP) that causes moderate to severe bone deformities. Type VII OI is characterized by fractures at birth, blue sclera, early deformity of the lower extremities, coxa vara, and osteopenia. There is no known cure for this disease. There are few definitions of craniofacial and oral manifestations of type VII OI available in the literature. The aim of this study was to improve the quality of life of a 6-year-old pediatric patient with primary dentition diagnosed with OI type VII by providing oral rehabilitation, and to offer qualified treatment alternatives to such patients.</p> Busra Tekin, Rusen Demir, Ebru Akleyin Copyright (c) 2024 Journal of Clinical Trials and Experimental Investigations https://creativecommons.org/licenses/by/4.0 https://jctei.com/index.php/jctei/article/view/102 Sat, 25 Mar 2023 00:00:00 +0300