Lichenoid drug eruption due to pirfenidone in a patient with idiopathic pulmonary fibrosis

Authors

DOI:

https://doi.org/10.5281/zenodo.13830529

Keywords:

Idiopathic pulmonary fibrosis, lichenoid drug eruption, pirfenidone

Abstract

Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disease of unknown cause characterized by relentless scarring in the lung parenchyma, leading to decreased quality of life and early mortality. Pirfenidone and nintedanib have been approved for the treatment of IPF based on their ability to slow functional decline and disease progression. Lichenoid drug eruption (LDE) refers to a drug-induced eruption resembling lichen planus, typically presenting as purple, symmetrical, eczematous plaques. While skin reactions due to pirfenidone have been reported in numerous cases, pirfenidone-induced LDE is rarely observed. In this case, we present a rare instance of pirfenidone-induced LDE.

References

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Yoo SA, Park HE, Kim M, Park HJ. A Case Report of Pirfenidone-Induced Lichenoid Drug Eruption in a Patient with Idiopathic Pulmonary Fibrosis. Ann Dermatol. April 2022;34(2):136-8.

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Published

2024-09-20

How to Cite

1.
Celik MS, Celik C, Cepik N, Ozercan MS. Lichenoid drug eruption due to pirfenidone in a patient with idiopathic pulmonary fibrosis. J Clin Trials Exp Investig [Internet]. 2024 Sep. 20 [cited 2024 Oct. 11];3(3):60-4. Available from: https://jctei.com/index.php/jctei/article/view/118